Patients taking WAKIX reported a significantly lower ESS score compared with patients taking placebo
A lower ESS score means a lower chance of dozing or falling asleep in everyday situations.
EDS Results
WAKIX was studied for the treatment of EDS in 159 adults with narcolepsy in two clinical trials (Trial 1 and Trial 2). WAKIX was compared with placebo (sugar pill) using the Epworth Sleepiness Scale (ESS)A questionnaire that measures the level of EDS by seeing how likely you are to doze or fall asleep in 8 everyday situations..
Their ESSEpworth Sleepiness Scale (ESS): A questionnaire that measures the level of EDS by seeing how likely you are to doze or fall asleep in 8 everyday situations. scores were 16 or higher, which means they had a high chance of dozing or falling asleep in everyday situations, such as:
A lower ESS score means a lower chance of dozing or falling asleep in everyday situations.
Everyone responds to medication differently. Individual responses varied in the clinical trials.
Cataplexy Results
WAKIX was studied for the treatment of cataplexy in 154 adults with narcolepsy in two clinical trials (Trial 3 and Trial 1). WAKIX was compared with placebo (sugar pill) by measuring how often patients in the trials experienced cataplexy. One trial measured the number of weekly cataplexy attacks and the other trial measured the number of daily cataplexy attacks.
Examples of cataplexy include:
Everyone responds to medication differently. Individual responses varied in the clinical trials.
Side Effects
In clinical trials of adults with narcolepsy, the most common side effects of WAKIX and at least twice the rate of placebo (sugar pill) were:
n indicates the number of patients who were treated with WAKIX or received placebo.
Other side effects of WAKIX in the clinical trials included increased heart rate, hallucinations, irritability, abdominal pain, sleep disturbance, and decreased appetite.
These are not all the possible side effects of WAKIX. Tell your healthcare provider about any side effect that bothers you or that does not go away.